Saturday, December 12, 2020

Why does exercise make people healthy and live longer? Mitophagy

Moderate to vigorous exercise can cause mitochondrial oxidative stress. 

The mitochondrial stress induced by aerobic exercise promotes the process of mitochondrial autophagy, 

that is, the muscles process damaged or dysfunctional mitochondria to maintain muscle health.


Autophagy, as the name implies, is "eat yourself." 

Autophagy is an evolutionarily conserved important process of turnover of intracellular substances in eukaryotes. In autophagy, 

some damaged proteins or organelles are encapsulated by autophagic vesicles, 

and then sent to lysosomes for degradation and recycling, thereby fulfilling the metabolic needs of the cell itself and the renewal of certain organelles. 

"Aerobic exercise can remove damaged mitochondria in skeletal muscle"


If you exercise regularly, you will continue to remove damaged mitochondria. Have healthy muscles with better mitochondrial quality.

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